• Neutralizing toxic oligomers

  • Meet us for partnering opportunities

  • Novel Alzheimer and amyloidosis treatment targets

  • Target oligomeric species using the crossbeta technology platform

  • Crossbeta Biosciences, Utrecht, the Netherlands

Intellectual Property

Crossbeta Biosciences Proprietary Technology

Over the past years Crossbeta Biosciences has build a portfolio of patents and patent applications that allows protection of its discoveries and inventions in several areas of applications.

 

Our main applications include:

  • Crossbeta Pathway (WO04004698) – granted

 

This patent, named the ‘Crossbeta Pathway’ application, was filed in July 2002, and discloses that the crossbeta structure is binding site for receptors and a signal triggering a clearance pathway for obsolete proteins, called the Crossbeta Pathway. Evidence is provided for the existence of crossbeta structures misfolded proteins and several crossbeta structure binding proteins, including receptors, such as RAGE, are also disclosed. It claims the use of crossbeta binding proteins for the detection and treatment of misfolded protein diseases.

  • Binding compounds (WO07008072) – granted

 

Filed in July 2005, this patent claims the selection of small compounds modulating binding of proteins to misfolded proteins for use for the treatment of misfolded protein diseases.



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